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DNA-PKCS (R4090)pAb

DNA-PKCS (R4090)pAb

Cat no: BS1092


Supplier: Bioworld Technology, Inc.
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The PIKrelated kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy termini that is not present in the PI 3- and PI 4-kinases. DNA-PK is a heterotrimeric DNA binding enzyme that is composed of a large subunit, DNA-PKCS, and two smaller subunits collectively known as Ku. The loss of DNA-PK leads to defects in DSB repair and V(D)J recombination. FRAP can autophosphorylate on serine and bind to Rapamycin/FKBP.
Catalogue number: BS1092
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P78527
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 4060-4110 of Human DNA-PKCS.
Species: DNA-PKCS (R4090) pAb detects endogenous levels of DNA-PKCS protein.
Molecular weight: ~ 450 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: DNA PKcs; DNA-PK catalytic subunit; DNA-PKcs; EC 2.7.11.1; DNPK1; p460; DNA Pkcs; DNA dependent protein kinase. DNA PK cs. catalytic subunit
Additional info: For research use only, not for use in diagnostic procedure.

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