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DNA pol alpha (K111) Peptide

DNA pol alpha (K111) Peptide

Cat no: BS1922P

Supplier: Bioworld Technology, Inc.
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DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases. DNA pol alpha, beta, delta and E are involved in DNA replication and repair. DNA pol delta and DNA pol E are multisubunit enzymes, with DNA pol delta consisting of two subunits: p125, which interacts with the sliding DNA clamp protein PCNA; and p50. The nuclear-encoded DNA pol gamma is the only DNA polymerase required for the replication of the mitochondrial DNA. DNA pol ? is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis. DNA pol 0 is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks.
Catalogue number: BS1922P
Applications: Block/Neutralize/Inhibit
Swiss prot: P09884
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide DNA pol alpha (K111). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; POLA1; POLA; DNA polalpha
Additional info: This peptide can be used with studies using BS1922 DNA pol alpha (K111) pAb.

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