DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases. DNA pol (alpha), (beta), (delta) and E are involved in DNA replication and repair. DNA pol (delta) and DNA pol E are multisubunit enzymes, with DNA pol (delta) consisting of two subunits