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DNA pol (delta) 3 pAb

DNA pol (delta) 3 pAb

Cat no: BS5699

Supplier: Bioworld Technology, Inc.
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DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol (alpha), (beta), (delta) and E. DNA pol (delta) and DNA pol E are multisubunit enzymes, with DNA pol (delta) consisting of two subunits which interact with the sliding DNA clamp protein PCNA. DNA pol (delta) 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol (delta).
Catalogue number: BS5699
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q15054
Dilutions: WB: 1:500~1:1000 ICC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to the 421-466 of Human DNA pol (delta) 3.
Species: DNA pol (delta) 3 pAb detects endogenous levels of DNA pol (delta) 3 protein.
Molecular weight: ~ 51 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: DNA polymerase delta subunit 3; DNA polymerase delta subunit p66; POLD3; KIAA0039; DNA pol (delta)3; DNA pol(delta)3; DNApol(delta)3; DNA pol (delta) p66; DNA pol(delta) p66
Additional info: For research use only, not for use in diagnostic procedure.

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