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DNA pol E 2 pAb

DNA pol E 2 pAb

Cat no: BS5700

Supplier: Bioworld Technology, Inc.
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DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. Exonucleases involved in these processes include DNA polymerases, including DNA pol (delta) and E. DNA pol (delta) consists of two subunits-p125 which interacts directly with the sliding DNA clamp protein PCNA, and p50. DNA pol (delta) can be regulated by cell cycle proteins. DNA pol E is a multiple subunit enzyme, the catalytic subunit of which is encoded by the POL2 gene. The exact reactions catalyzed by DNA pol (delta) and E on leading and lagging strands have not yet been elucidated.
Catalogue number: BS5700
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P56282
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 144-189 of Human DNA pol E 2.
Species: DNA pol E 2 pAb detects endogenous levels of DNA pol E 2 protein.
Molecular weight: ~ 60 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: DNA polymerase epsilon subunit 2; DNA polymerase II subunit 2; DNA polymerase epsilon subunit B; POLE2; DPE2; DNA pol E2; DNA pol EB; DNA pol E B; DNA polE2; DNApolE2; DNA polEB; DNApolEB;
Additional info: For research use only, not for use in diagnostic procedure.

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