DNAM-1 (Y325) Peptide

DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

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SPECIFICATIONS

Catalog Number

AP0431P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide DNAM-1 (Y325). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q15762

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using AP0431 DNAM-1 (Y325) pAb.

Alternative Names

adhesion glycoprotein; CD226 antigen; CD226 molecule; DNAM 1; DNAM1; DNAX accessory molecule 1; platelet and T cell activation antigen 1; PTA1; T lineage specific activation antigen 1 antigen; TLiSA1;