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Drosha Peptide

Cat no: BS60422P

Drosha Peptide

The ribonuclease III superfamily represents a structurally distinct group of double-strand-specific endonucleases with essential roles in RNA maturation, RNA decay, and gene silencing. Initial cleavage of microRNAs is catalysed by Drosha, a nuclease of the RNase III family, which acts on primary miRNA transcripts (pri-miRNAs) in the nucleus. Human Drosha is a component of two multi-protein complexes. The larger complex contains multiple classes of RNA-associated proteins including RNA helicases, proteins that bind double-stranded RNA, novel heterogeneous nuclear ribonucleoproteins and the Ewing's sarcoma family of proteins. The smaller complex is composed of Drosha and the double-stranded-RNA-binding protein, DGCR8.

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SPECIFICATIONS

Catalog Number

BS60422P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Drosha. (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q9NRR4

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS60422 Drosha pAb.

Alternative Names

Ribonuclease 3; Protein Drosha; Ribonuclease III; RNase III; p241; DROSHA; RN3, RNASE3L; RNASEN

SUPPLIER INFO

Bioworld Technology, Inc.

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