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EAAT1 (K541) pAb

EAAT1 (K541) pAb

Cat no: BS2925

Supplier: Bioworld Technology, Inc.
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Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic acction of glutamate. The reuptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. Three glutamate transporters have been identified in human brain, designated EAAT1-3. EAAT1 and EAAT3 are also expressed in various non-nervous tissues, while EAAT2 expression appears to be restricted to the brain.
Catalogue number: BS2925
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P43003
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 500-600 of Human EAAT1.
Species: EAAT1 (K541) pAb detects endogenous levels of EAAT1 protein.
Molecular weight: ~ 60 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Excitatory amino acid transporter 1; Sodium-dependent glutamate/aspartate transporter 1; GLAST-1; Solute carrier family 1 member 3; EAAT1; GLAST; GLAST1; SLC1A3
Additional info: For research use only, not for use in diagnostic procedure.

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