EAAT1 (K541) Peptide

Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic acction of glutamate. The reuptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. Three glutamate transporters have been identified in human brain, designated EAAT1-3. EAAT1 and EAAT3 are also expressed in various non-nervous tissues, while EAAT2 expression appears to be restricted to the brain.

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SPECIFICATIONS

Catalog Number

BS2925P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide EAAT1 (K541). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P43003

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2925 EAAT1 (K541) pAb.

Alternative Names

Excitatory amino acid transporter 1; Sodium-dependent glutamate/aspartate transporter 1; GLAST-1; Solute carrier family 1 member 3; EAAT1; GLAST; GLAST1; SLC1A3