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Elongin A3 (E403) Peptide

Cat no: BS2412P

Elongin A3 (E403) Peptide

The elongin (SIII) complex is composed of a transcriptionally active A subunit and two small regulatory subunits, B and C. This complex stimulates the transcription elongation rate of RNA polyermase II by suppressing time spent at template-encoded arresting sites along DNA. Elongin A3, also known as RNA polymerase II transcription factor SIII subunit A3 and Transcription elongation factor B polypeptide 3C, is a 546 amino acid nuclear protein that functions as a general transcription elongation factor that increases RNA polymerase II transcription elongation and forms a stable complex with Elongin BC. In contrast to Elongin A, transcriptional activity of Elongin A3 is not stimulated by Elongin BC. Elongin A3 contains one TFIIS N-terminal domain and is ubiquitously expressed in human tissue.

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SPECIFICATIONS

Catalog Number

BS2412P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Elongin A3 (E403). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q8NG57

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2412 Elongin A3 (E403) pAb.

Alternative Names

TCEB3C; Elongin-A3; Elongin A3; ElonginA3; EloA3; TCEB3L2

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