EMR4 (I140) pAb

FIRE is a 689 amino acid protein that maps to human gene EMR4. FIRE is also known as EGF-like module-containing mucin-like hormone receptor-like 4 and is a member of the the G protein-coupled receptor 2 family, LN-TM7 subfamily. The epidermal growth factor-transmembrane seven (EGF-TM7) family are proteins that express EGF-like domains at their extracellular N-terminus coupled to a classical seven-transmembrane (TM7) cassette. FIRE is believed to mediate the cellular interaction between myeloid cells and (beta) cells. FIRE is a membrane bound, multi-pass protein that is proteolytically cleaved into two subunits, an extracellular (alpha) subunit and a seven-transmembrane subunit. FIRE contains one GPS (G protein-coupled receptor proteolytic cleavage site) domain and two EGF (epidermal growth factor)-like domains, the second of which mediates the interaction with the putative ligand.

Prices direct from Bioworld Technology, Inc.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

BS2792

Size

100ug/100ul

Applications

IF, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 108-164 of Human EMR4.

Species

EMR4 (I140) pAb detects endogenous levels of EMR4 protein.

Dilutions

WB: 1:500~1:1000\nIF: 1:50~1:200

Swiss Prot

Q86SQ3

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 51 kDa

Alternative Names

Putative EGF-like module-containing mucin-like hormone receptor-like 4; EGF-like module receptor 4; G-protein coupled receptor 127; G-protein coupled receptor PGR16; EMR4; GPR127; PGR16; EMR4P; FIRE