ENPP3 Peptide

Ecto-nucleotide pyrophosphatase/phospho-diesterase-I enzymes (E-NPP), a group of type II transmembrane proteins, cleave phosphodiester and phosphosulfate bonds in deoxynucleotides, NAD, and nucleotide sugars. There exist three closely related proteins in mammalian species: E-NPP1 (PC-1), E-NPP2 (PDNP2), and E-NPP-3, also known as CD203c, each expressed in different cells or at different locations in the same cells. Basophils, a type of major proinflammatory effector cells involved in diverse pathologic reactions, exhibit CD203c expression. For instance, CD203c expression increases in response to a variety of allergens, including cat dander, latex, and bee and wasp venom. Hovever, these allergies are not the only condition associated with CD203c upregulation; CD203c upregulation may also serve as a tumor marker for colon carcinoma.

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SPECIFICATIONS

Catalog Number

BS60438P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide ENPP3. (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

O14638

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS60438 ENPP3 pAb.

Alternative Names

Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; E-NPP 3; ENPP 3; ENPP-3; E-NPP3; Phosphodiesterase I beta; PD-Ibeta; Phosphodiesterase I/nucleotide pyrophosphatase 3; CD203c; Alkaline phosphodiesterase I; Nucleotide pyrophosphatase; NPPase; PDNP3