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Eos (R507) Peptide

Cat no: BS9253P

Eos (R507) Peptide

Members of the Ikaros family contain zinc-finger domains that are involved in DNA-binding and in the formation of homodimers and heterodimers between Ikaros family members. Eos, also known as zinc finger protein Ikaros 4, is a 585 amino acid transcriptional repressor. Localized to the nucleus, Eos may play a role in the development of the central and peripheral nervous systems. Eos self-associates, forms heterodimers with Ikaros family members and interacts with CtBP2, PU.1 and MITF to repress transcription of cathepsin K and TRAP promoters. Eos is expressed at low levels in kidney, thymus, liver and heart, and at high levels in skeletal muscle.

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SPECIFICATIONS

Catalog Number

BS9253P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Eos (R507). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q9H2S9

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS9253 Eos (R507) pAb.

Alternative Names

EOS; Eos protein; IKAROS family zinc finger 4 (Eos); IKAROS family zinc finger 4; Ikaros family zinc finger protein 4; IKZF4; ZNFN1A4;

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