EPHX1 pAb

Cat no: BS6593

Supplier: Bioworld Technology, Inc.

0 reviews | Write a Review Pencil

Description
Additional Information

Epoxide hydrolases (EHs) are biotransformation enzymes that catalyze the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. The enzymatic hydration is essentially irreversible and produces mainly metabolites of lower reactivity that can be conjugated and excreted, and, therefore, are generally regarded as detoxifying. Microsomal EH (mEH) is one of many enzymes involved in the metabolism of endogenous levels of and exogenous toxicants such as tobacco-derived carcinogens. mEH exhibits a broad substrate specificity, while the soluble EH (sEH) is an enzyme with a "complementary" substrate specificity to mEH. The mEH protein is encoded by the EPHX1 gene, which maps to chromosome 1q42.12. Polymorphism of the EPHX1 gene is a risk factor ovarian cancer and hepatocellular carcinoma.

Catalogue number:	BS6593
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunofluorescence, Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	P07099
Dilutions:	WB: 1:500~1:2000 IHC: 1:50~1:200 IF: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Recombinant full length Human EPHX1.
Species:	EPHX1 pAb detects endogenous levels of EPHX1 protein.
Molecular weight:	~ 53 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	EPHX 1; EPHX; EPHX1; EPOX; Epoxide hydratase; Epoxide hydrolase 1; Epoxide hydrolase 1 microsomal (xenobiotic); Epoxide hydroxylase 1; Epoxide hydroxylase 1 microsomal (xenobiotic); HYEP; HYL1; MEH; Microsomal epoxide hydrolase;
Additional info:	For research use only, not for use in diagnostic procedure.

See Full Product Listings >

EPHX1 pAb

Cat no: BS6593

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from Bioworld Technology, Inc.




By submitting this form you agree to your details being passed to Bioworld Technology, Inc. for the purpose of generating the best quote*