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ER(alpha) (K531) pAb

ER(alpha) (K531) pAb

Cat no: BS1535

Supplier: Bioworld Technology, Inc.
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Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor uperfamily of ligand-activated transcription factors. Estrogen receptors, ncluding ER(alpha) and ER(beta), contain DNA binding and ligand binding domains nd are critically involved in regulating the normal function of reproductive issues. ER(alpha) and ER(beta) have been shown to be differentially activated by various igands. Receptor-ligand interactions trigger a cascade of events, including issociation from heat shock proteins, receptor dimerization, phosphorylation nd the association of the hormone activated receptor with specific regulatory lements in target genes. Evidence suggests that ER(alpha) and ER(beta) may be egulated by distinct mechanisms even though they share many functional characteristics.
Catalogue number: BS1535
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P03372
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 501-550 of Human ER(alpha).
Species: ER-(alpha) (K531) pAb detects endogenous levels of ER-(alpha) protein.
Molecular weight: ~ 66 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Estrogen receptor; ER-alpha; ER; ESR1; ESR; NR3A1
Additional info: For research use only, not for use in diagnostic procedure.

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