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ER(beta) (E101) pAb

ER(beta) (E101) pAb

Cat no: AP0436

Supplier: Bioworld Technology, Inc.
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Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER(alpha) and ER(beta), contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ER(alpha) and ER(beta) have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER(alpha) and ER(beta) may be regulated by distinct mechanisms even though they share many functional characteristics.
Catalogue number: AP0436
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q92731
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 71-120 of Human ER(beta).
Species: ER(beta) (E101) pAb detects endogenous levels of ER(beta) protein.
Molecular weight: ~ 48, 60 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: DKFZp686N23123; ER alpha; ER; ER-alpha; Era; ESR 1; ESR; ESR1; ESR1; ESRA; Estradiol receptor; Estrogen nuclear receptor alpha; Estrogen receptor 1; Estrogen receptor alpha 3*; 4; 5; 6; 7*/822 isoform; Estrogen receptor alpha delta 3*; 4; 5; 6; 7*; 8*/941 isoform; Estrogen receptor alpha delta 3*; 4; 5; 6; 7*/819 2 isoform; Estrogen receptor alpha delta 4 +49 isoform; Estrogen receptor alpha delta 4*; 5; 6; 7*/654 isoform; Estrogen receptor alpha delta 4*; 5; 6; 7; 8*/901 isoform; Estrogen receptor; Major OR
Additional info: For research use only, not for use in diagnostic procedure.

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