ERbeta (E101) Peptide

Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERalpha and ERbeta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ERalpha and ERbeta have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERalpha and ERbeta may be regulated by distinct mechanisms even though they share many functional characteristics.

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SPECIFICATIONS

Catalog Number

AP0436P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide ERbeta (E101). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q92731

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using AP0436 ERbeta (E101) pAb.

Alternative Names

DKFZp686N23123; \nER alpha; \nER; \nER-alpha; \nEra; \nESR 1; \nESR; \nESR1; \nESR1; \nESRA; \nEstradiol receptor; \nEstrogen nuclear receptor alpha; \nEstrogen receptor 1; \nEstrogen receptor alpha 3*; 4; 5; 6; 7*/822 isoform; \nEstrogen receptor alpha delta 3*; 4; 5; 6; 7*; 8*/941 isoform; \nEstrogen receptor alpha delta 3*; 4; 5; 6; 7*/819 2 isoform; \nEstrogen receptor alpha delta 4 +49 isoform; \nEstrogen receptor alpha delta 4*; 5; 6; 7*/654 isoform; \nEstrogen receptor alpha delta 4*; 5; 6; 7; 8*/901 isoform; \nEstrogen receptor; \nMajor OR