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ERdj3 (K66) Peptide

ERdj3 (K66) Peptide

Cat no: BS3114P

Supplier: Bioworld Technology, Inc.
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Members of the heat shock protein 40 (HSP 40) family of proteins all contain a highly conserved J domain that associates with HSP 70 and regulates the function of HSP 70 by activating its adenosine triphosphatase activity. ERdj3, an HSP 40 chaperone, is expressed in the ER lumen, where it interacts with BiP, a molecule involved in retrotranslocating proteins out of the ER. ERdj3 also associates with several other protein substrates, including unfolded light chains, a nonsecreted Ig light chain mutant and a VSV-G ts045 mutant. Shiga toxin (Stx) is a bacterial tool that enzymatically inactivates the 28S rRNA, inhibiting protein synthesis of infected cells. Stx also interacts with ERdj3 and Sec 61 to form a complex through which proteins are retrotranslocated to the cytoplasm. ERdj3 may play a role in the ER quality control system.
Catalogue number: BS3114P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9UBS4
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide ERdj3 (K66). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: DnaJ homolog subfamily B member 11; APOBEC1-binding protein 2; ABBP-2; ABBP2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-interacting protein 4; DNAJB11; EDJ; ERJ3; HDJ9; PSEC0121; UNQ537/PRO1080
Additional info: This peptide can be used with studies using BS3114 ERdj3 (K66) pAb.

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