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ERK3 (D475) Peptide

ERK3 (D475) Peptide

Cat no: BS2662P

Supplier: Bioworld Technology, Inc.
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Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl2 and caspase 3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK3 gene maps to chromosome 15q21 and encodes a 721 amino acid protein.
Catalogue number: BS2662P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q16659
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide ERK3 (D475). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: MAPK6; DKFZP686F03189; EC 2.7.11.24; ERK-3; ERK3; HST17250; P97MAPK; PRKM6
Additional info: This peptide can be used with studies using BS2662 ERK3 (D475) pAb.

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