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ERK8 (D171) Peptide

ERK8 (D171) Peptide

Cat no: BS2438P


Supplier: Bioworld Technology, Inc.
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The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.
Catalogue number: BS2438P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q8TD08
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide ERK8 (D171). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Extracellular signal-regulated kinase 8; MAPK15; Mitogen-activated protein kinase 15
Additional info: This peptide can be used with studies using BS2438 ERK8 (D171) pAb.

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