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ETAR (D424) Peptide

ETAR (D424) Peptide

Cat no: BS3165P

Supplier: Bioworld Technology, Inc.
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Endothelin receptor A (ETAR), also known as EDNRA, ET1 receptor, ETA, EDN1 and ET-AR, is a member of the guanine-binding regulatory protein-coupled receptor family. ETAR binds endothelins and has the highest affinity for its ligand, ET1, as compared to the ETBR receptor. Both ET receptors, ETAR and ETBR, are activated by ET1, which results in inhibition of active lens sodiumpotassium transport. Activation of the ET receptors also causes an increase in cytoplasmic calcium concentration in cultured lens epithelial cells. In addition, ETAR induces arachidonic acid accumulation. ETAR has seven hydrophobic transmembrane domains and is expressed in aorta, lung, atrium, kidney, placenta and prostate. Specifically, placental vascular smooth muscle cells (PVSMCs) exclusively express ETAR.
Catalogue number: BS3165P
Applications: Block/Neutralize/Inhibit
Swiss prot: P25101
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide ETAR (D424). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: EDNRA; ET-A; ETA; ETA-R; ETRA
Additional info: This peptide can be used with studies using BS3165 ETAR (D424) pAb.

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