Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (eIF2AK4, GCN2, General Control Nonderepressible 2)

Cat no: E8949-18

Supplier: United States Biological

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Additional Information

GCN2 is a sensor of amino acid deprivation. GCN2 was recently found to regulate lipid metabolism during leucine deprivation in addition to regulating amino acid metabolism. (1) Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western blot: 1:5000-1:15,000 Immunoprecipitation: 2-5ug/ml of lysate Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	E8949-18
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunoprecipitation, Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris-citrate/phosphate buffer, pH 7-8, 0.09% sodium azide.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
Alternative names:	eIF2AK4, GCN2, General Control Nonderepressible 2
References:	1. Guo, F. (2007) Cell Metabolism, 5:103-114.
Additional info:	Recognizes human Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (eIF2AK4, GCN2, General Control Nonderepressible 2)

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Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (eIF2AK4, GCN2, General Control Nonderepressible 2)

Cat no: E8949-18

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