Home  >  Products  >  F1Aa, CT (Protein Fem-1 Homolog B, FEM1b, FEM1-beta, F1A-alpha, Fem-1-like Death Receptor-binding Protein alpha, Fem-1-like in Apoptotic Pathway Protein alpha, FEM1B, F1AA, KIAA0396)
F1Aa, CT (Protein Fem-1 Homolog B, FEM1b, FEM1-beta, F1A-alpha, Fem-1-like Death Receptor-binding Protein alpha, Fem-1-like in Apoptotic Pathway Protein alpha, FEM1B, F1AA, KIAA0396)

F1Aa, CT (Protein Fem-1 Homolog B, FEM1b, FEM1-beta, F1A-alpha, Fem-1-like Death Receptor-binding Protein alpha, Fem-1-like in Apoptotic Pathway Protein alpha, FEM1B, F1AA, KIAA0396)

Cat no: F0001-05A

Supplier: United States Biological
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Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aa and FEM1b. F1Aa/FEM1b is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aa is cleaved by CED-3 and caspase. FEM-1/F1Aa associates with CED-4 and its mammalian homologue Apaf-1. Overexpression of F1Aa /span>induces apoptosis. F1Aa /span>is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aa /span>is expressed in a variety of human and mouse tissues. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F0001-05A
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Chan SL, Tan KO, Zhang L, 2. Ventura-Holman T, Maher JF. Sequence, organization, and expression of the human FEM1B gene. Biochem Biophys Res Commun 2000;267(1):317-20.
Additional info: Recognizes human F1Aa (CT). Species Crossreactivity: mouse and rat.

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