FABP2 pAb

?Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). Intestinal FABP (I-FABP) is an abundant cytosolic protein abundant in small intestine epithelial cells. The human gene maps to chromosome 4q26 and has a polymorphism at codon 54, which confers an alanine-encoding allele and a threonine-encoding allele. Threonine at position 54 is associated with increased fat oxidation and Insulin resistance.

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SPECIFICATIONS

Catalog Number

BS6602

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human FABP2.

Species

FABP2 pAb detects endogenous levels of FABP2 protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

P12104

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~15 kDa

Alternative Names

FABP 2; FABP2; FABPI; FABPI; Fatty acid binding protein 2 intestinal; Fatty acid binding protein; Fatty acid binding protein intestinal; Fatty acid-binding protein 2; Fatty acid-binding protein; I FABP; I-FABP; IFABP; intestinal; Intestinal fatty acid binding protein 2; Intestinal-type fatty acid-binding protein; MGC133132; OTTHUMP00000163925;