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FAM3C (Protein FAM3C, Interleukin-like EMT Inducer, ILEI, GS3786)

FAM3C (Protein FAM3C, Interleukin-like EMT Inducer, ILEI, GS3786)

Cat no: F2954-15C1

Supplier: United States Biological
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FAM3C is a 227aa secretory protein that belongs to a novel cytokine-like family with sequence similarity to FAM3 family. FAM3C is a signaling cytokine with a GG domain, hydrophobic leader sequence and an N-terminal signal peptide. FAM3C has a cytokine activity and shows a change in expression in pancreatic cancer-derived cells. It is ubiquitously expressed in most of the tissues. Reports suggest that FAM3C plays an important role in inner ear development and may thus be involved in cell differentiation and proliferation during inner ear embryogenesis. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Immunohistochemistry (formalin fixed paraffin embedded): 5-10ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human, mouse and rat brain Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F2954-15C1
Reactivities: Human, Bovine, Canine, Chicken/Bird, Non-Human Primate
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Zhu, Y. et al. Genomics. 80:144-150 (2002). 2. Pilipenko, VV. et al. Gene. 335:159-168 (2004).
Additional info: Recognizes human FAM3C. Species Crossreactivity: bovine, canine, chicken, monkey. Species sequence homology: mouse, rat, chimpanzee, pufferfish, opossum.

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