Home  >  Products  >  FAP-1 (Tyrosine-protein Phosphatase Non-receptor Type 13, Fas-associated Protein-tyrosine Phosphatase 1, PTP-BAS, Protein-tyrosine Phosphatase 1E, PTP-E1, hPTPE1, Protein-tyrosine Phosphatase PTPL1, PTPN13, PNP1, PTP1E, PTPL1)
FAP-1 (Tyrosine-protein Phosphatase Non-receptor Type 13, Fas-associated Protein-tyrosine Phosphatase 1, PTP-BAS, Protein-tyrosine Phosphatase 1E, PTP-E1, hPTPE1, Protein-tyrosine Phosphatase PTPL1, PTPN13, PNP1, PTP1E, PTPL1)

FAP-1 (Tyrosine-protein Phosphatase Non-receptor Type 13, Fas-associated Protein-tyrosine Phosphatase 1, PTP-BAS, Protein-tyrosine Phosphatase 1E, PTP-E1, hPTPE1, Protein-tyrosine Phosphatase PTPL1, PTPN13, PNP1, PTP1E, PTPL1)

Cat no: F0019-53N5

Supplier: United States Biological
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A novel protein tyrosine phosphatase, Fap-1 (for FAS- associated phosphatase) (originally designated PTP- BAS), has been shown to associated with the carboxyl terminus 15aa of FAS. Three isoforms of the protein result from alternative RNA splicings, the longest of which encodes a protein 2485aa in length. Although lacking a transmembrane region, Fap-1 does contain a membrane-binding domain, similar to that found in cytoskeletonassociated proteins such as ezrin. Fap-1 does not seem to associate with CD40 or death domain proteins such as TNF-RI and TNF-RII. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 1:100 for 30min at RT Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10min followed by cooling at RT for 20min. Optimal dilutions to be determined by the researcher. Positive Control: Placenta Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F0019-53N5
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human FAP-1.

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