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FAST (R410) Peptide

FAST (R410) Peptide

Cat no: BS3463P

Supplier: Bioworld Technology, Inc.
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The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states. FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4. Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues. FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGbeta and activin, indicating that these FAST proteins mediate TFGbeta induced signal transduction.
Catalogue number: BS3463P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q14296
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide FAST (R410). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: FOXH1; FAST-1; FAST-2; FAST1; FAST2; HFAST-1
Additional info: This peptide can be used with studies using BS3463 FAST (R410) pAb.

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