FBG3 (F-box 3)

Cat no: F0019-98D2

Supplier: United States Biological

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F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	F0019-98D2
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ul
Form:	As reported
P type:	Pab
Purity:	As reported
References:	Ilyin,G.P. et al. Gene. 2002 Aug 21;296(1-2):11-20.
Additional info:	FBG3 protein. Species Crossreactivity: Human. Cross-reactivity with rat and mouse is likely due to high homology (94%) between the immunogen and these rodent sequences.

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FBG3 (F-box 3)

Cat no: F0019-98D2

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