FBN1 (N2843) Peptide

Cat no: BS1127P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

The fibrillin family of proteins, including fibrillin-1 (FBN1) and fibrillin-2 (FBN2), are integral components of a distinct subset of extracellular microfibrils. Microfibrils are found in elastic tissues where they facilitate elastic fiber formation and in nonelastic tissue where they support the association of the epithelial cells with the interstitial matrix. Characteristic of the fibrillin proteins are the epidermal growth factor (EGF)-like motifs, which contain a consensus sequence for calcium binding. This calcium association may be critical for protein-protein interactions and stabilization of the microfibrils. Mutations of the FBN1 gene have been shown to result in Marfan syndrome, a disease characterized by abnormal synthesis, secretion and matrix deposition of fibrillin. FBN2 is also linked to a rare, yet similiar, skeletal disorder, congenital contractural arachnodactyly.

Catalogue number:	BS1127P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P35555
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide FBN1 (N2843). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Fibrillin-1; Fibrillin1; FBN1; FBN
Additional info:	This peptide can be used with studies using BS1127 FBN1 (N2843) pAb.

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FBN1 (N2843) Peptide

Cat no: BS1127P

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