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FBP3 (R241) Peptide

FBP3 (R241) Peptide

Cat no: BS3297P

Supplier: Bioworld Technology, Inc.
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Activation of FUSE, the far-upstream element, is required for the proper expression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP (FUSE-binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL60 cells, FBP, FBP2, and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxylterminal activation domains. Expression of FBP is detected in undifferentiated cells and is substantially decreased following cellular differentiation.
Catalogue number: BS3297P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q96I24
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide FBP3 (R241). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Far upstream element-binding protein 3; FUSE-binding protein 3; FUBP3; FBP3
Additional info: This peptide can be used with studies using BS3297 FBP3 (R241) pAb.

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