Home  >  Products  >  FbxL3 (F-box and Leucine-rich Repeat Protein 3, FBL3, FBL3A, FBXL3A, F-box and Leucine-rich Repeat Protein 3A, F-box Protein Fbl3a)
FbxL3 (F-box and Leucine-rich Repeat Protein 3, FBL3, FBL3A, FBXL3A, F-box and Leucine-rich Repeat Protein 3A, F-box Protein Fbl3a)

FbxL3 (F-box and Leucine-rich Repeat Protein 3, FBL3, FBL3A, FBXL3A, F-box and Leucine-rich Repeat Protein 3A, F-box Protein Fbl3a)

Cat no: F0022-95

Supplier: United States Biological
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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F0022-95
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: Albig AR, Neil JR, Schiemann WP. Fibulins 3 and 5 antagonize tumor angiogenesis in vivo.Cancer Res. 2006 Mar 1;66(5):2621-9. PMID: 16510581
Additional info: Species Crossreactivity: Human. Other species not tested.

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