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FCGR1A pAb

FCGR1A pAb

Cat no: BS6238

Supplier: Bioworld Technology, Inc.
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Three different classes of IgG Fc receptors have been described: Fc(gamma)RI (CD64), Fc(gamma)RII (CD32) and Fc(gamma)RIII (CD16). The low affinity receptors, CD64 and CD16, have a putative role in mediating humoral immune responses. CD64 is a surface glycoprotein with high affinity for monomeric IgG, is expressed constitutively on monocytes and macrophages, and can be induced in neutrophils subsequent to IFN-(gamma) stimulation. CD64 plays a putative role in the initiation of cell-mediated cytotoxicity. Thus far, three genes encoding four distinct CD64 transcripts have been described. CD64 has been shown to associate with signal transducing subunit of the high affinity IgE receptor. Src family kinases Hck and Lyn show increased kinase activity and will co-immunoprecipitate with CD64 subsequent to receptor cross linking.
Catalogue number: BS6238
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P12314
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human FCGR1A.
Species: FCGR1A pAb detects endogenous levels of FCGR1A protein.
Molecular weight: ~39,43 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: CD64; CD64A; Fc fragment of IgG high affinity Ia receptor (CD64); Fc gamma receptor; Fc gamma receptor I A1; Fc gamma RI; Fc gamma RIA; Fc-gamma RI; Fc-gamma RIA; FCG1; FcgammaRIa; FCGR1; FCGR1; FCGR1A; FcRI; FLJ18345; High affinity immunoglobulin gamma Fc receptor I; IGFR1; IgG Fc receptor I;
Additional info: For research use only, not for use in diagnostic procedure.

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