FEN1 (Flap Endonuclease 1, FEN-1, DNase IV, Flap Structure-specific Endonuclease 1, Maturation Factor 1, MF1, hFEN-1, RAD2)

Cat no: F0046-01

Supplier: United States Biological

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Description
Additional Information

FEN-1 is a 42kD protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	F0046-01
Reactivities:	Human
Hosts:	Mouse
Applications:	Immunohistochemistry, Western Blot
Size:	50ug
Form:	Supplied as a liquid in PBS.
P type:	Mab
Isotype:	IgG1
Purity:	Purified by Protein G affinity chromatography.
Additional info:	Recognizes human FEN1.

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FEN1 (Flap Endonuclease 1, FEN-1, DNase IV, Flap Structure-specific Endonuclease 1, Maturation Factor 1, MF1, hFEN-1, RAD2)

Cat no: F0046-01

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