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Fer (D798) Peptide

Cat no: BS1936P

Fer (D798) Peptide

Fer is a non-receptor protein-tyrosine kinase (nRTK) of the Fes/Fps family, which shares a functional (SH2) domain and is involved in signaling pathways through receptor tyrosine kinases (RTK) and cytokine receptors. The Fes/Fps family is distinct from c-Src, c-Abl and related nRTKs and was originally distinguished as a homolog to retroviral oncoproteins. In vivo, Fer kinaseassembles into homotrimers via conserved coiled-coil domains. The N-terminal coiled-coil domains of Fer can autophosphorylate in trans, thereby regulating their cellular function through differential phosphorylation states. Growth factor exposure can induce tyrosine phosphorylation of Fer and recruitment of Fer to RTK complexes containing p85. Fer is implicated in insulin signaling, cell-cell signaling, human prostatic proliferative diseases, and is involved in the regulation of G1 progression.

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SPECIFICATIONS

Catalog Number

BS1936P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Fer (D798). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P16591

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1936 Fer (D798) pAb.

Alternative Names

FERD3L; DROSOPHILA; FER3-LIKE; MGC119861; N-TWIST; NATO3; NTWIST

SUPPLIER INFO

Bioworld Technology, Inc.

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