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Fes (K161) pAb

Fes (K161) pAb

Cat no: BS2464


Supplier: Bioworld Technology, Inc.
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FES is a protooncogene that encodes a protein-tyrosine kinase distinct from c-Src, c-Abl and other nonreceptor tyrosine kinases. FES was originally identified as the cellular homolog of several transforming retroviral oncoproteins. FES plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell-cell interaction. Genetic analysis using transgenic mouse model implicate FES in the regulation of inflammation and innate immunity. FES modulates the innate immune response of macrophages to LPS challenge, in part, by regulating the internalization and down-regulation of the TLR4 receptor complex.
Catalogue number: BS2464
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P07332
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 131-180 of Human Fes.
Species: Fes (K161) pAb detects endogenous levels of Fes protein.
Molecular weight: ~ 80 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Proto-oncogene tyrosine-protein kinase FES/FPS; C-FES
Additional info: For research use only, not for use in diagnostic procedure.

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