FGF10, CT (FGF10, Fibroblast growth factor 10, Keratinocyte growth factor 2)

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

035614

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Stein, J.L., et al. Neuroimage 53(3):1160-1174(2010)\nMostowska, A., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(7):538-545(2010)\nChattopadhyay, I., et al. Mutat. Res. 696(2):130-138(2010)\nJugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :\nYokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :

Additional Info

Human

Alternative Names

FGF10, Fibroblast growth factor 10, Keratinocyte growth factor 2