FGF20, CT (FGF20, Fibroblast growth factor 20) (APC)

The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

035622-APC

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Mouse

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Allophycocyanin (APC).

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

de Mena, L., et al. Neurosci. Lett. 479(1):22-25(2010)\nRose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :\nLemaitre, H., et al. J. Neurosci. 30(17):5992-5997(2010)\nMaity, H., et al. Curr Pharm Biotechnol 10(6):609-625(2009)\nKalinina, J., et al. Mol. Cell. Biol. 29(17):4663-4678(2009)

Additional Info

Mouse

Alternative Names

FGF20, Fibroblast growth factor 20