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FGFR1 OP (N371) pAb

FGFR1 OP (N371) pAb

Cat no: BS1123

Supplier: Bioworld Technology, Inc.
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FOP, also known as FGFR1OP (FGFR1 oncogene partner), is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
Catalogue number: BS1123
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: O95684
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 341-390 of Human FGFR1 OP.
Species: FGFR1OP (N371) pAb detects endogenous levels of FGFR1OP protein.
Molecular weight: ~ 43, 92 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: FGFR1 oncogene partner; FGFR1OP; Fibroblast growth factor receptor 1 oncogene partner; FOP
Additional info: For research use only, not for use in diagnostic procedure.

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