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FGR (Tyrosine-protein Kinase Fgr, Proto-oncogene c-Fgr, p55-Fgr, SRC2)

Cat no: F4149-02A

FGR (Tyrosine-protein Kinase Fgr, Proto-oncogene c-Fgr, p55-Fgr, SRC2)

Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcriptional activity of the nuclear receptor with which they associate. One such coactivator is Steroid Receptor Coactivator-2 (SRC2).\n\nApplications:\nSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:10,000\nWestern Blot: 1:500-1:2000\nImmunohistochemistry (Formalin fixed paraffin embedded): 1:200\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

F4149-02A

Size

50ul

Applications

ELISA, IHC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid, 0.03% sodium azide.

P Type

Mab

Purity

Ascites

Isotype

IgG1

Additional Info

Recognizes human FGR. Species sequence homology: Mouse.

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