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FIAF (Fasting-induced Adipose Factor, Angiopoietin-like Protein 4, ANGPTL 4, PPAR gamma Angiopoitein-related Protein, PGAR, Hepatic Fibrinogen Angiopoietin-related Protein, HFARP, Bk89, Ng27, PPARG, fibrinogen Angiopoietin Related protein, major histocomp

Cat no: F4165-01A

FIAF (Fasting-induced Adipose Factor, Angiopoietin-like Protein 4, ANGPTL 4, PPAR gamma Angiopoitein-related Protein, PGAR, Hepatic Fibrinogen Angiopoietin-related Protein, HFARP, Bk89, Ng27, PPARG, fibrinogen Angiopoietin Related protein, major histocomp

The fasting-induced adipose factor (FIAF, ANGPTL4, PGAR, HFARP) was previously identified as a novel adipocytokine that was up-regulated by fasting, by peroxisome proliferators- activated receptor agonists, and by hypoxia. FIAF and other adipocytokines including resistin, adiponectin, acylationstimulating protein, plasminogen activator inhibitor-1, rennin angiotensin system, metallothioneins and tumor growth factor-b have been implicated in a variety of different processes, ranging from blood pressure control to lipid metabolism and insulin senziting. It has been tempting to attribute many of the clinical abnormalities associated with obesity from insulin resistance to altered secretion of particular adipocytokines.\n\nApplications: \nSuitable for use in ELISA. Other applications not tested.\n\nRecommended Dilution: \nELISA: 1:32000\nWestern Blot: 0.5ug/ml. ~ 26kD in Mouse Liver and Rat Liver lysates after antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 45.5kD according to mouse NP_065606.1.\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

F4165-01A

Size

100ug

Applications

ELISA

Hosts

Goat

Reactivities

Mouse, Rat

Form

Supplied as a liquid in Tris-saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

References

1. Lichtenstein L, Berb

Additional Info

Recognizes mouse Angptl4. Species Crossreactivity: Rat.

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