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FIBP, Recombinant, Human, aa1-364, His-Tag (Acidic Fibroblast Growth Factor Intracellular-binding Protein, FGFIBP, FIBP-1)

Cat no: 137058

FIBP, Recombinant, Human, aa1-364, His-Tag (Acidic Fibroblast Growth Factor Intracellular-binding Protein, FGFIBP, FIBP-1)

Acidic fibroblast growth factor intracellular-binding protein isoform a, also known as FIBP, is a member of Fibroblast growth factors (FGFs) represent a family. FGF activity influences development, adult tissue homeostasis, angiogenesis and cancer progression. FIBP is a 364 amino acid protein that binds to internalized FGF-1 and is thought to be involved in mitogenic function of FGF-1. FIBP localizes to the nucleus and is highly expressed in heart, skeletal muscle and pancreas and at lower levels in brain, placenta, liver and kidney. \n\nSource: \nRecombinant protein corresponding to human FIBP, fused to His-tag at N-terminal expressed in E.coli.\n\nMolecular Weight: \n~44.3kD (387aa) (MALDI-TOF)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSMTSELDI FVGNTTLIDE DVYRLWLDGY SVTDAVALRV RSGILEQTGA TAAVLQSDTM DHYRTFHMLE RLLHAPPKLL HQLIFQIPPS RQALLIERYY AFDEAFVREV LGKKLSKGTK KDLDDISTKT GITLKSCRRQ FDNFKRVFKV VEEMRGSLVD NIQQHFLLSD RLARDYAAIV FFANNRFETG KKKLQYLSFG DFAFCAELMI QNWTLGAVGE APTDPDSQMD DMDMDLDKEF LQDLKELKVL VADKDLLDLH KSLVCTALRG KLGVFSEMEA NFKNLSRGLV NVAAKLTHNK DVRDLFVDLV EKFVEPCRSD HWPLSDVRFF LNQYSASVHS LDGFRHQALW DRYMGTLRGC LLRLYHD\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137058

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0,10% glycerol.

Purity

~95% (SDS-PAGE)

References

1. Kolpakova, E. et al: Biocham J. 1998, 336:213-222. 2. Volkin, D.B et al: Biotechnol.. 1996, 9:181-217.

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Applications

ELISA

Reactivities

Hum

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Applications

IF

Hosts

Mouse

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Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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