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FIBROBLAST GROWTH FACTOR-21 (FGF 21)

FIBROBLAST GROWTH FACTOR-21 (FGF 21)

Cat no: F4212-93C

Supplier: United States Biological
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FGF 21 is a critical metabolic regulator which signals through FGF receptors 1c and 4, to stimulate the uptake of glucose by adipocytes, in the presence of the protein cofactor betaKlotho, and in conjunction with the up-regulation of glucose transporter 1 (GLUT1). Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:2000 Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: Rabbit Anti Goat IgG (Fc) FITC, HRP Recommended Useful Reagents: HUMAN LIVER TOTAL PROTEIN LYSATE Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F4212-93C
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in TBS, pH 7.3, 0.02% sodium azide, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human FGF 21 (Fibroblast growth factor-21), a 22kD secreted growth factor and member of the heparin-binding growth factor family, in human liver cell lysates at ~22kD.

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