Home  >  Products  >  Fibronectin (FN, Cold-insoluble Globulin) (Biotin)
Fibronectin (FN, Cold-insoluble Globulin) (Biotin)

Fibronectin (FN, Cold-insoluble Globulin) (Biotin)

Cat no: F4215-54J

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
This antibody is well suited to detect extracellular matrix proteins in normal as well as disease state tissues. Disruption of tissue organization is the hallmark of neoplasia. Malignant lesions can be distinguished from benign by examining the breakdown of basement membranes and loss of 3-dimensional architecture. Malignant cells are presumed to use matrix metalloproteases to degrade barriers created by the extracellular matrix which then allows metastasis to occur. Collagenases, stomelysins and gelatinases can collectively degrade all of the various components of the extracellular matrix, including fibrillar and non-fibrillar collagens and basement membrane glycoproteins. Cellular Localization: Extracellular matrix. Applications: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry (paraffin-embedded sections). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F4215-54J
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugates: Biotin
Size: 100ug
Form: 0.01M Na phosphate, 0.25M NaCl, pH7.6, 15mg/ml BSA. Label with Biotin.
P type: Pab
Isotype: IgG
Purity: Whole antisera
Alternative names: DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, Fibronectin 1, FINC, FN 1, FN1, LETS, MSF, Transformation Sensitive Protein
Additional info: negligible crossreactivity with Type I, II, III, IV, V or VI Collagens or Laminin. Non-specific cross reaction of anti-Fibronectin antibodies with other human serum proteins or non-Fibronectin extracellular matrix proteins is negligible. Species Crossreactivity: Crossreacts with Human. Expected to crossreact with most Mammals due to sequence homology.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave