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FKBP1A pAb

FKBP1A pAb

Cat no: BS6608

Supplier: Bioworld Technology, Inc.
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Immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases which bind to and mediate the effects of immunosuppressive drugs such as Cyclosporin, FK506 and Rapamycin. The prototypic member of the family, FKBP12, was originally identified as a target of FK506 and Rapamycin activity. FKBP12 is an abundant, evolutionarily conserved cytoplasmic protein. Although the molecular role of FKBP12 activity is not well understood, the protein has been implicated as a regulator of diverse array of cellular processes including T cell activation, entry into the cell cycle and intracellular calcium release. Interestingly, FKBP12 has been shown to associate with the intracellular cytoplasmic domain of the type I TGF(beta) receptor. This association is constitutive and not dependent on the activation of the receptor.
Catalogue number: BS6608
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P62942
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human FKBP1A.
Species: FKBP1A pAb detects endogenous levels of FKBP1A protein.
Molecular weight: ~ 12 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: 12 a FK506-binding protein; 12 a FKBP; FK506 binding protein 1; FK506 binding protein 12; FK506 binding protein 1A 12 a; FK506 binding protein 1A; FK506 binding protein T cell 12; FK506-binding protein 1A; FKB1A; FKBP 12; FKBP 1A; FKBP-12; FKBP-1A; FKBP1; FKBP12; FKBP12 Exip3; FKBP12C; FKBP1A; Immunophilin FKBP12; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP1A; PKC12; PKCI2; PPIase; PPIase FKBP1A; Protein kinase C in
Additional info: For research use only, not for use in diagnostic procedure.

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