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Flotillin-2 (R144) Peptide

Cat no: BS2878P

Flotillin-2 (R144) Peptide

Flotillins belong to a family of lipid raft-associated integral membrane proteins that carry a evolutionarily conserved domain called the prohibitin homology domain (PHB). Flotillin members are ubiquitously expressed and located to non-caveolar microdomains (lipid rafts) on the cell plasma membrane where they support signal transduction and regulate lipid raft motility and localization. Two flotillin members have been described, flotillin-1 and flotillin-2. In addition to its colocalization with lipid rafts on the plasma membrane, flotillin-1 also has been found at compartments of the endocytic and autophagosomal pathways, such as recycling/late endosomes, the Golgi complex, as well as the nucleus. Flotillin-2 is mainly localized to the plasma membrane and is prevalent in cell-cell contact sites. However, overexpressed flotillin-2 has also been found in the late endosome. Both flotillin-1 and flotillin-2 are commonly used as lipid raft associated markers.

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SPECIFICATIONS

Catalog Number

BS2878P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Flotillin-2 (R144). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q14254

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2878 Flotillin-2 (R144) pAb.

Alternative Names

Flotillin-2; Epidermal surface antigen; ESA; Membrane component chromosome 17 surface marker 1; ESA1; M17S1; FLOT2

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