FMR1 (Fragile X Mental Retardation 1 Protein, FMRP, Protein FMR-1)

Cat no: F6072-01A

Supplier: United States Biological

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Fragile X Mental Retardation Protein (FMRP) is an RNA-Binding protein that is associated to polysomes and may be involved in the transpot of mRNA from the nucleus to the cytoplasm. Defects in FMR1 are the cause of Fragile X syndrome, which is a common genetic disease characterized by moderate to severe mental retardation, macroorchidism, large ears, prominent jaw, and high-pitched, jocular speech. The defect in most fragile X syndrome patients results from an amplication of a CGG repeat regions with is directly in front of the coding region. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.1-0.3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: KELLY cell lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	F6072-01A
Reactivities:	Human
Hosts:	Goat
Applications:	Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type:	Pab
Isotype:	IgG
Purity:	Purified by immunoaffinity chromatography.
Additional info:	Recognizes human FMR1. Species sequence homology: canine, mouse, rat.

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FMR1 (Fragile X Mental Retardation 1 Protein, FMRP, Protein FMR-1)

Cat no: F6072-01A

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