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FOXA2 (Forkhead Box A2, Hepatocyte Nuclear Factor 3 beta, HNF-3-beta, HNF3B, HNF-3B, MGC19807, Transcription Factor 3B, TCF3B, TCF-3B) (AP)

Cat no: F9045-11B-AP

FOXA2 (Forkhead Box A2, Hepatocyte Nuclear Factor 3 beta, HNF-3-beta, HNF3B, HNF-3B, MGC19807, Transcription Factor 3B, TCF3B, TCF-3B) (AP)

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.\n\nApplications: \nSuitable for use in ELISA, Immunofluorescence and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:500-1:1000\nELISA: 1ug/ml-3ng/ml\nOptimal dilutions to be determined by the researcher.\n\nHybridoma: \nSp2/0 myeloma cells with spleen cells from Balb/c mice.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C with the addition of glycerol. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive.

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SPECIFICATIONS

Catalog Number

F9045-11B-AP

Size

100ul

Applications

ELISA, IF, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Alkaline Phosphatase.

P Type

Mab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG2a

Additional Info

Recognizes human FOXA2.

Alternative Names

Forkhead Box Protein A2, Hepatic Nuclear Factor 3 beta

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