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FoxA3, ID (Fork Head Domain Protein FKD2, foxa3, fkd2)

FoxA3, ID (Fork Head Domain Protein FKD2, foxa3, fkd2)

Cat no: F9045-22

Supplier: United States Biological
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Forkhead box A3 (foxa3) is a member of the fox gene family, a functionally diverse group of transcription regulators. The fox gene family has been evolutionarily conserved and plays a role in such biological processes as development, differentiation and metabolism. In mammals, the hepatocyte nuclear factors 3alpha, -beta and -gamma (HNF-3) are respectively encoded by foxa1, -a2 and -a3. Gene expression studies have demonstrated that HNF3 proteins play a critical role in regulation of early-onset type 2 diabetes genes and of glucagons transcription and pancreatic alpha-cell function. In zebrafish embryos, FoxA3 and Goosecoid coexpressed at the dorsal blastula margin are necessary for the determination of anterior neural fate. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Control Peptide: F9045-22P Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F9045-22
Reactivities: Zebrafish/Fish
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 250ul
Form: Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Navas, MA et al (2000) Hum. Hered. 50:370-381. 2. Shen, W et al (2001) J. Biol. Chem. 276(46);42812-7. 3. Seiliez, Iban et al (2006) Dev. Biol. 290(1):152-163.
Additional info: Recognizes zebrafish FoxA3.

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