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FoxE3 (R97) Peptide

Cat no: BS2304P

FoxE3 (R97) Peptide

The human forkhead-box (FOX) gene family consists of at least 43 members, including FOXE3, a 288-amino acid protein. FOXE3 is a winged-helix transcription factor that plays a crucial role during the initial stages of lens development and closure of the lens vesicle. FOXE3 may also act as a factor that promotes survival and proliferation while preventing differentiation in the lens epithelium. As the posterior cells of the lens fiber begin to differentiate, expression of FOXE3 is limited to the undifferentiated cells coating the anterior surface of the lens. Congenital primary aphakia (CPA) is a rare developmental disorder caused by a null mutation in the FOXE3 gene that is identified by the absence of a lens. The development of CPA is normally stimulated during the fourth or fifth week of human embryogenesis.

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SPECIFICATIONS

Catalog Number

BS2304P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide FoxE3 (R97). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q13461

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2304 FoxE3 (R97) pAb.

Alternative Names

Forkhead box protein E3; Forkhead-related protein FKHL12; Forkhead-related transcription factor 8; FREAC-8; FKHL12; FREAC8; FOXE3

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