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FPR1 (I207) pAb

FPR1 (I207) pAb

Cat no: BS5719

Supplier: Bioworld Technology, Inc.
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The N-formyl peptide receptor (FPR) is a chemotactic G protein-coupled receptor (GPCR) that is found on the surface of phagocytic leukocytes, such as neutrophils and monocytes. The human FPR family comprises three members, FPR, FPRL1 (also designated lipoxin A4 receptor) and FPRL2, and each family member contains specific residues, which are responsible for determining its ligand specificity. FPR, a seven transmembrane-domain receptor, primarily binds the chemoattractant N-formyl-methionyl-leucyl-phenylalanine (fMLP), which activates several biological processes, including chemotaxis, transcriptional activation, and actin reorganization. FPR also mediates the inhibition of neutrophil migration through binding to specific peptide fragments of annexin I, which causes calcium transients and affects inflammatory responses.
Catalogue number: BS5719
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P21462
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to the 207-252 of Human FPR1.
Species: FPR1 (I207) pAb detects endogenous levels of FPR1 protein.
Molecular weight: ~ 38 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; Short name=FPR; N-formylpeptide chemoattractant receptor
Additional info: For research use only, not for use in diagnostic procedure.

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